林产化学与工业2012，Vol.32Issue(5)：1-6,6.
脱氢枞胺及其Schiff碱衍生物与DNA作用的研究
DNA-Binding Studies of Dehydroabietylamine and Its Schiff Base Derivatives
摘要
Abstract
N-[ ( pyridin-2-ylmethylene )-imino ] dehydroabietylamine schiff base (L2) and its reduced form ( L3 ) were synthesized and characterized by elemental analysis,IR spectra,'H NMR and MS techniques. The interaction between individual compound and salmon sperm DNA was investigated by UV,fluorescence and circular dichroism (CD) spectroscopic and viscosity analysis. Results show that all the three compounds bind to DNA by intercalation mode,and the schiff base is the strongest binding agent among them.关键词
脱氢枞胺/Schiff碱/DNA作用Key words
dehydroabietylamine/schiff base/DNA interaction分类
化学化工引用本文复制引用
费宝丽,李雯,张典,夏兵,龙剑英,刘庆波..脱氢枞胺及其Schiff碱衍生物与DNA作用的研究[J].林产化学与工业,2012,32(5):1-6,6.基金项目
南京林业大学引进高层次留学回国人员科研基金(163030031) （163030031）
南京大学配位化学重点实验室开放基金(无编号) （无编号）
江苏高校优势学科建设工程资助项目(无编号) （无编号）
