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MRI和磁共振波谱在肝性脑病的应用价值

赵红领 高绚照 刘惠萍 马连萍

临床神经病学杂志2012,Vol.25Issue(4):266-268,3.
临床神经病学杂志2012,Vol.25Issue(4):266-268,3.

MRI和磁共振波谱在肝性脑病的应用价值

Application value of MRI and proton magnetic resonance spectroscopy in hepatic encephalopathy

赵红领 1高绚照 1刘惠萍 1马连萍1

作者信息

  • 1. 453000 河南省新乡市中心医院神经内科
  • 折叠

摘要

Abstract

Objective To investigate the application value of MRI and pruum magnetic resonance spectroscopy ('H-MRS) in hepatic encephalopathy (HE). Methods MRI and ' H-MRS examination were applied in 6 HE patients. The peaks of N-acelyl aspartate ( NAA) , Creatine ( Cr) , Cholines (Cho) , glutamine compounds ( Glx) , myo-inositol (mI) in basal nuclei were measured, and the ratio of Cho, mI, NAA and Cr were compulered. The results were compared with 5 normal controls. Results MRI was showed that then: were high signal on T, WI in bilateral basal nuclei in all the 6 HE patients, including involved internal capsule in 1 case., caudate nucleus in 2 cases, tegmental in I case. There were no obvious abnormal signal on T2WI in 5 cases, but widely high signal on T2W1 in 1 case caused by diffuse cerebral edema. ' H-MRS was showed that the peaks of Cho, mI, ratio of Cho/Cr and mI/Cr in HE group were significantly lower than those in normal control group, the peak of Glx was significantly higher than normal control group, (P<0. 01 -0.005). There was no statistical significance in NAA/Cr between the two groups. Conclusions MRI shows thai high signal on T1 WI in bilateral basal nuclei is the characteristics of HE. 'H-MRS can reflect metabolism changes more aceulately.

关键词

肝性脑病/磁共振成像/磁共振波谱

Key words

hepatic encephalopathy/ magnetic resonance imaging/ magnetic/ resonance spectruscopy

分类

医药卫生

引用本文复制引用

赵红领,高绚照,刘惠萍,马连萍..MRI和磁共振波谱在肝性脑病的应用价值[J].临床神经病学杂志,2012,25(4):266-268,3.

临床神经病学杂志

OA北大核心CSTPCD

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