中国临床保健杂志2012，Vol.15Issue(4)：371-373,3.DOI:10.3969/J.issn.1672-6790.2012.04.013
叶酸联合阿托伐他汀对轻度认知功能障碍的疗效
Observations on the efficacy of folic acid and atorvastatin in treating mild cognitive impairment
摘要
Abstract
Objective To assess the efficacy of folic acid and atorvastatin in treating mild cognitive impairment. Methods 77 people using MMSE scales were allocated to MCI groups, 32 healthy people were as controls ( control group). MCI groups were randomly allocated to folic acid and atorvastatin group and control group. Evaluation was made using MMSE scales in every groups after treatment, A comparison was made between pretreatment and postt-reatment and between the two groups. Results After treatment,there were no significant differences in blood Hcy.TC and MMSE scores in group A (P ＞ 0. 05). In group B, MMSE scores was lower than before after treatment (P ＜ 0. 05). Blood Hey and TC level were higher than before after treatment,but there was no significant different (P＞0. 05). In group C, MMSE scores was lower than before, but there was no significant difference (P ＞ 0. 05). Blood Hey and TC level were significant lower than those before treatment (P ＜0.05). Conclusion Patients with mild cognitive impairment have a rapid decline of cognitive function. Folic acid combine with atorvastatin has an obvious advantage in improving their cognitive function.关键词
认知障碍/叶酸/降血脂药/治疗结果Key words
Cognition disorders/Folic acid/Antilipemic agents/Treatment outcome分类
医药卫生引用本文复制引用
顾辨辨,严光,周树生,孙梦雯,柏慧..叶酸联合阿托伐他汀对轻度认知功能障碍的疗效[J].中国临床保健杂志,2012,15(4):371-373,3.基金项目
安徽省国际科技合作计划项目(11030603025) （11030603025）
