环境与职业医学2012，Vol.29Issue(9)：543-547,5.
塑料瓶装饮料中邻苯二甲酸二丁酯和邻苯二甲酸-(2-乙基己基)酯含量及其对大学生的潜在暴露风险
Dibutyl Phthalate and Di(2-ethylhexyl)phthalate Contents in Plastic Packaged Beverages and Potential Exposure Risk to College Students
摘要
Abstract
[ Objective ] To estimate the exposure levels to dibutyl phthalate (DBP) and di(2-ethylhexyl)phthalate (DEHP) from plastic packaged beverages among college students. [ Methods ] The chronic daily intake and margin of safety of DBP and DEHP were estimated by the gas-chromatography-determined concentrations of DBP and DEHP in 114 brands of plastic packaged beverages, and the drinking patterns among 196 college students were collected via an online questionnaire using convenience sampling strategy. Monte Carlo models were applied to simulate the daily exposures to DBP and DEHP in target students and related sensitive analyses were also performed. [ Results ] The daily intakes of plastic packaged beverages varied, but the plastic packaged drinking water accounted for the largest proportion both in males and females. The contents of DBP and DEHP also varied with beverage categories, but coffee, milk, and juice beverages showed relatively higher contents. The chronic daily intakes of DBP and DEHP were less than corresponding tolerable daily intakes, and the margins of safety were both less than 1. According to the results of Monte Carlo simulation, 99.90% of the students interviewed were within the safe range of DBP exposure through plastic packaged beverages, and the rest 0.10% were at potential risks of reproductive and developmental toxicities. The probabilities of reproductive and developmental toxicity risks were 0.02% for male students and 0.09% for female students. No health risks should be concerned at the exposure levels of DEHP in sampled beverages. [ Conclusion ] The intake levels of DBP via plastic packaged beverages may pose potential risks of reproductive and developmental toxicities to college students; however, that of DEHP is within the safe range.关键词
邻苯二甲酸二丁酯/邻苯二甲酸-(2-乙基己基)酯/塑料瓶装饮料/风险评估/蒙特卡洛模型Key words
dibutyl phthalate/ di(2-ethylhexyl)phthalate/ plastic packaged beverages/ risk assessment/ Monte Carlo model分类
医药卫生引用本文复制引用
陈莉莉,李荔群,张励倩,陈波,厉曙光..塑料瓶装饮料中邻苯二甲酸二丁酯和邻苯二甲酸-(2-乙基己基)酯含量及其对大学生的潜在暴露风险[J].环境与职业医学,2012,29(9):543-547,5.基金项目
国家自然科学基金资助项目(编号:81172673) （编号:81172673）
