南京师大学报（自然科学版）2012，Vol.35Issue(2)：66-71,6.
聚(3,4-乙烯基二氧噻吩)/碳纳米管复合膜修饰电极的电化学制备及其用于8-羟基-2'-脱氧鸟嘌呤核苷的检测
Electrochemical Preparation of Poly (3, 4-Ethylenedioxythiophene)/Carbon Nanotubes Composite Film Modified Electrode and Its Application to Determination of 8-Hydroxy-2'-Deoxyguanosine
摘要
Abstract
The poly(3, 4-ethylenedioxythiophene)/carbon nanotubes (CNTs) composite film was prepared on the glassy carbon electrode surface by one-step galvanostatic deposition and used for the study of the electrochemical behavior of 8-hydroxy-2'-deoxyguanosine (8-OH-dG). The experimental results showed that the hybrid film can combine the advantages of conductivity of PEDOT and the unique electronic performance of CNTs and effectively enhance the adsorption and electrochemical oxidation of 8-OH-dG. Moreover, this proposed hybrid film modified electrode also showed excellent re-producibility and stability in the experiment. In 0. 1 mol/L pH 9. 0 phosphate buffer solution, the oxidative peak currents of 8-OH-dG had two good linear relationships with its concentration in 0. 014 - 14 μmol/L and 14 -56 μmol/L, with the detection limit of 35 nmol/L (S/N = 3).关键词
8-羟基-2'-脱氧鸟嘌呤核苷/聚(3,4-乙烯基二氧噻吩)/碳纳米管/导电聚合物/尿酸Key words
8-Hydroxy-2'-deoxyguanosine/ poly(3 /4-ethylenedioxythiophene) / carbon nanotubes/ conductive polymer/ uric acid分类
化学化工引用本文复制引用
潘吉超,姚飞,任腾飞,贾丽萍,贾文丽,崔慧,王怀生..聚(3,4-乙烯基二氧噻吩)/碳纳米管复合膜修饰电极的电化学制备及其用于8-羟基-2'-脱氧鸟嘌呤核苷的检测[J].南京师大学报（自然科学版）,2012,35(2):66-71,6.基金项目
国家自然科学基金(21075059)、山东省“泰山学者”建设工程专项经费资助. （21075059）
