畜牧与饲料科学2012，Vol.33Issue(8)：87-88,2.
ChIP在研究DNA与蛋白质相互作用中的应用
Application of ChIP in Study on the Interaction between DNA and Protein
祝铁钢1
作者信息
- 1. 衡水学院生命科学系,河北衡水053000
- 折叠
摘要
Abstract
The interaction between DNA and protein is one important field of gene expression regulation in the post-genome era. There are many methods to study the interaction between DNA and protein at present, but chromatin immunoprecipitation assay (CHIP) is more suitable comparing with them. Besides, cloning technique and DNA chip technology could be combined to high-throughput screen the unknown DNA targets of known protein factors and study the distribution of trans-acting factors in whole genome so as to enhance the development and occurrence of DNA-protein interaction regulatory networks. The research progress of ChIP was introduced, and its prospect was prospected.关键词
染色质免疫沉淀技术/克隆技术/靶序列/组蛋白Key words
chromatin immunoprecipitation assay/cloning technique/target sequence/histone分类
生物科学引用本文复制引用
祝铁钢..ChIP在研究DNA与蛋白质相互作用中的应用[J].畜牧与饲料科学,2012,33(8):87-88,2.
