农业环境科学学报2012，Vol.31Issue(9)：1672-1676,5.
微囊藻毒素缺氧/厌氧降解产物Adda对秀丽线虫的毒性
Toxicities of Adda Produced During Microcystin Anoxic/Anaerobic Degradation to Caenorhabditis elegans
摘要
Abstract
Recent studies have shown that micocystins(MCs) can be degraded by indigenous bacteria from lake sediments under anoxic/ anaerobic conditions. Unlike aerobic MCs degradation, in which MCs are completely decomposed, anoxic/anaerobic degradation can produce and accumulate one product Adda. Up to now, however, little is known about the toxicities of this product. To assess the safety of anoxic/ anaerobic degradation of MCs, the toxicities of Adda were investigated using Caenorhabditis elegans(C. elegans) as the animal model. Our results showed that exposure to low dose Adda(not more than 0.05 μmol·L‐1) had no negative effect on C. elegans. Exposure to Adda of 0.1 μmol · L‐1 could lead to significant defects of head and body locomotion, whereas no negative effect was observed for other functions at the same dosage, suggesting that locomotion ability of C. elegans was more susceptible to Adda than other tested functions. All tested functions except for the rate of vulva abnormality of C. elegans were significantly negatively affected when exposed to Adda of 0.5 μmol · L‐1. These results suggest that Adda is far less toxic than MCLR and biodegradation under anoxic/anaerobic conditions can detoxify MCs efficiently. However, the high concentration of Adda may still pose new risks to ecosystem if it accumulates in natural environment during MCs anoxic/anaer-obic degradation.关键词
微囊藻毒素/Adda/厌氧降解/毒性Key words
microcystin/ adda/ anaerobic degradation/ toxicity分类
资源环境引用本文复制引用
陈晓国,吴小燕,章伟成..微囊藻毒素缺氧/厌氧降解产物Adda对秀丽线虫的毒性[J].农业环境科学学报,2012,31(9):1672-1676,5.基金项目
国家自然科学基金项目(21077083) （21077083）
中央高校基本科研业务费专项资金资助(2012-Ⅳ-095) （2012-Ⅳ-095）
