农业环境科学学报2012，Vol.31Issue(9)：1759-1764,6.
利用离体方法评价典型污染土壤的芳烃受体干扰效应和甲状腺受体干扰效应
Toxicity Assessment of Typical Contaminated Soil Based on AhR Disruptors and TR Disruptors in Vitro
摘要
Abstract
The AhR disrupting effect and TR disrupting effect of 13 typical pollution soils from three provinces (Hunan Province, Sichuan Province, Liaoning Procince) were assessed by using the ethoxyresorfin O-deethylase bioassay and receptor bioassay. The results showed the AhR disrupting effect of 13 typical pollution soil ranged from 4.2 pg·g‐1 to 23.9 pg·g‐1 2、3 、7、8-TCDD;None of them showed thyroid receptor inductive activities,but four samples showed thyroid receptor antagonistic activities (the TR disrupting effect ranged from 51~183 μg NH3·g‐1 dry soil). Two kinds of contamination might exist in the same area. Combined EROD test and TR yeast test can be an effective way to assess the potential ecological risks of complex environmental samples.关键词
芳烃受体干扰效应/甲状腺受体干扰效应/EROD测试/重组基因酵母测试Key words
AhR disrupting effect/ TR disrupting effect/ EROD bioassay/ recombinant gene yeast bioassay分类
资源环境引用本文复制引用
李莉,李娜,周建国,饶凯峰..利用离体方法评价典型污染土壤的芳烃受体干扰效应和甲状腺受体干扰效应[J].农业环境科学学报,2012,31(9):1759-1764,6.基金项目
国家高技术研究发展计划(863计划)(2009AA06Z402) （863计划）
国家自然科学基金(40801204,20871042) （40801204,20871042）
高等学校博士学科点专项科研基金(20104104110004) （20104104110004）
