青岛大学医学院学报2012，Vol.48Issue(5)：405-407,3.
中国人群蔬菜摄入及饮酒与直肠癌发病关系Meta分析
Meta-ANALYSIS ON RELATIONSHIP BETWEEN VEGETABLE INTAKE OR WINE DRINKING AND RECTAL CANCER IN CHINESE PEOPLE
邢茜宜 1周晓彬 1陈静 2张超英 1高永丽 3魏延其4
作者信息
- 1. 青岛大学医学院预防医学系,山东青岛266021
- 2. 青岛大学医学院图书馆
- 3. 青岛大学医学院附属医院
- 4. 武安市疾病控制中心
- 折叠
摘要
Abstract
Objective To investigate the relationship between vegetable intake or alcohol and rectal cancer in Chinese people, and provide a prevention of this malignancy. Methods The published case-control studies from 1990 to 2010 about correlation of vegetable intake or alcohol consumption with rectal cancer in China were searched in VIP and Wanfang database, the data retrieved from literature were analyzed using Meta-analysis method. Results On vegetable intake: eight reports were collected, of which, six reports, a total of 2 837 cases and 5 668 controls, were brought into Meta analysis. No consistency was found among the six studies (Q=65. 71,P<0. 05). Combined OR of vegetables (random effect model) was 0. 69 (95%CI:0. 51 — 0. 93) , m= 182. On alcohol consumption, nine reports were searched, eight were brought into Meta analysis, a total of 3 233 cases and 5 102 controls included. No consistency was detected among the eight studies (Q=31. 30,P<0. 05). The combined OR of alcohol (random effect model) was 1. 03 (95%CI:0. 98 — 1. 08) , m = 62. Conclusion This meta-analysis suggests that ingestion of vagetables is a protection of rectal cancer. People who took more vegetables had 0. 69 times risk of being suffered from the cancer compared with those taking less vagetables. The association between alcohol drinking and rectal cancer has not been confirmed.
关键词
直肠肿瘤/蔬菜/饮酒/Meta分析Key words
rectal neoplasms/ vegetables/ alcohol drinking/ Meta-analysis分类
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邢茜宜,周晓彬,陈静,张超英,高永丽,魏延其..中国人群蔬菜摄入及饮酒与直肠癌发病关系Meta分析[J].青岛大学医学院学报,2012,48(5):405-407,3.
