山东中医药大学学报2012，Vol.36Issue(5)：445-448,4.
钩藤总生物碱有效部位质量控制研究
Study on quality control of total alkaloids in Ramulus Uncariae Cum Uncis
摘要
Abstract
Objective:To establish the method for quality control of total alkaloids in Ramulus Uncariae Cum Uncis. Methods;The contents of total alkaloids were determined by acid dye colorimetry,HPLC was used to measure the contents of rhynchophylline and fingerprint of total alkaloids in Ramulus Uncariae Cum Uncis. Results:The contents of total alkaloids were higher than 50%,the linear range of rhynchopHylline was 5.75-92 μg/mL,the average recovery was 98.82%. The chemical composition of different batches total alkaloids in Ramulus Uncariae Cum Uncis was difference by fingerprint similarity evaluation. Conclution:The method can be used for quality control of total alkaloids in Ramulus Uncariae Cum Uncis.关键词
钩藤总生物碱/钩藤碱/指纹图谱Key words
total alkaloids in Ramulus Uncariae Cum Uncis/rhynchophylline/fingerprint分类
医药卫生引用本文复制引用
蒋海强,窦月,周洪雷..钩藤总生物碱有效部位质量控制研究[J].山东中医药大学学报,2012,36(5):445-448,4.基金项目
山东省科技发展计划项目(编号:2008GG2NS02011) （编号:2008GG2NS02011）
国家科技重大专项重大新药创制、山东省重大新药创制中心建设(编号:2009ZX09301-013) （编号:2009ZX09301-013）
山东省自然科学基金项目(编号:ZR2010HM017) （编号:ZR2010HM017）
山东省教育厅科技计划项目(编号:J105LL05) （编号:J105LL05）
国家自然科学基金项目(编号:810727941H2708). （编号:810727941H2708）
