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精浆锌含量与精液质量及体外受精结局的相关性

江莉 李慕军 牛冉冉 翟丹梅 袁华

山东医药2012,Vol.52Issue(35):22-24,3.
山东医药2012,Vol.52Issue(35):22-24,3.

精浆锌含量与精液质量及体外受精结局的相关性

Correlation between seminal plasma Zinc concentration and semen quality,outcomes of in vitro fertilization

江莉 1李慕军 1牛冉冉 1翟丹梅 1袁华1

作者信息

  • 1. 广西医科大学第一附属医院,南宁530021
  • 折叠

摘要

Abstract

Objective To investigate the relationship between seminal plasma Zinc concentration and sperm quality, outcomes of in vitro Fertilization. Methods The seminal plasma Zinc concentration of 81 infertile men was detected by using 5-Br-PAPS staining method. Spearman correlation between seminal plasma Zinc, conventional semen parameters and IVF fertilization rates, cleavage rate, and good quality embryo rate was analyzed. Results A significant positive correlation was found between seminal plasma Zinc concentration with sperm density, motility and IVF fertilization rate (r =0.49, 0. 305, 0.289; all P < 0.05) ; but was negatively correlated with immature sperm rate (r = -0. 278,P < 0. 05). However, no correlation was found between seminal plasma Zinc concentration and cleavage rate, good quality embryo rate( all P >0. 05 ). Conclusion Amount of seminal plasma zinc level can promote the maturation of sperm nuclear. Seminal plasma zinc content can decrease sperm density and motility, and also can decrease IVF fertilization rate; but no significant impact can be seen to the normal sperm morphology, IVF embryo cleavage rate and quality rate.

关键词

精浆,锌/精液质量/体外受精

Key words

seminal plasma, Zinc/ semen parameters/ in vitro fertilization

分类

医药卫生

引用本文复制引用

江莉,李慕军,牛冉冉,翟丹梅,袁华..精浆锌含量与精液质量及体外受精结局的相关性[J].山东医药,2012,52(35):22-24,3.

基金项目

广西卫生厅重点科研课题(桂卫重200846) (桂卫重200846)

广西教育厅高等学校科研项目(200103YB023). (200103YB023)

山东医药

OACSTPCD

1002-266X

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