摘要
Abstract
Objective :To observe efficacy of Danhong Injection for Treatment of chronic renal insufficiency caused by lower urinary tract obstruction. Methods: Forty - four patients with chronic renal insufficiency ( chronic reflux nephropathy ) underwent urinary catheteriza-tion or bladder pneumatic lithotripsy to relieve urinary tract obstruction before randomization. Then 23 patients took Danhong Injection, and were compared with other 21 patients in terms of kidney function assessment ( urea nitrogen 、creatinine ), renal arterial resistive Index ( RI) and pulsatility index (PI) assessed by CDFI, GFR assessed by ECT, etc. Results: After treatment both groups had significant improvement in urea nitrogen, creatinine, RI, PI, GFR (P<0.05). Compared with those of the; control group, the; treatment group had lower levels of plasma creatinine, RI, PI, and increased GFR (P<0.05 ). Conclusion: Danhong Injection can treat chronic renal insufficiency ( chronic reflux nephropathy ) caused by lower urinary tract obstruction, and it is recommendable in clinical application.关键词
丹红注射液/尿路梗阻/慢性肾功能不全Key words
Danhong Injection/ Urinary tract obstruction/ Chronic renal insufficiency