实用医学杂志2012，Vol.28Issue(13)：2187-2190,4.DOI:10.3969/j.issn.1006-5725.2012.13.033
DSA引导下背根节脉冲射频治疗带状疱疹后神经痛的疗效及安全性
Dosal root ganglion pulsed radiofrequency guided by DSA for postherpetic neuralgia
摘要
Abstract
Objective To observe the efficacy and safety of dosal root ganglion (DRG) pulsed radiofrequency for treating postherpetic neuralgia (PHN) guided by digital subtraction angiography (DSA). Methods 60 patients with PHN were randomly divided into two groups (each n= 30). Patients in Group A were treated with gabapentin, amitriptyline, and oxycodone, and patients in Group B were treated with DRG pulsed radiofrequency guided by DSA along with the same medicines used in Group A. VAS and oxycodone dosage before and 1d, 7 d, 30 d, 90 d, and 180 d after treatment, and side effects and complications during the treatment in the two groups were recorded. Results The VAS of patients in Group A and B before and Id, 7 d, 30 d, 90 d, 180 d after treatment were (8.2 ± 1.7) vs. (8.1 ± 1.6), (6.3 ± 1.8) vs. (4.5 ± 1.6), (4.1 ± 1.4) vs. (3.0 ± 1.2), (3.2 ± 1.5) vs. (2.1 ± 1.1), (3.1 ± 1.2) vs. (1.8 ±0.9), and (2.6 ±1.1) vs. (1.5 ±0.9), respectively (all P<0.05), and the oxycodone dosages were (28.8 ± 5.5) mg vs.(29.1 ± 5.8) mg, (35.6 ± 8.5) mg vs. (17.6 ± 5.4) mg, (42.3 ± 8.9) mg vs (12.4 ± 3.8) mg, (18.6 ± 4.3) mg vs. (5.1 ± 1.6) mg, (10.7 ± 2.4) mg vs. (6.0±1.3) mg, and (8.1 ± 1.6) mg vs. (4.2 ± 0.9) mg, respectively (all P < 0.05). The medicine side effects in Group B were obviously reduced, and no serious complications occurred. Conclusion DRG pulsed radiofrequency guided by DSA could rapidly relieve the pain of patients with PHN, reduce oxycodone dosage and its relative side effects, and may be a safe and effective method for treating PHN.关键词
疱疹,带状/神经痛/脉冲射频/背根节/DSAKey words
Herpes zoster/ Neuralgia/ Pulsed radiofrequency/ DRG/ DSA引用本文复制引用
黄乔东,宫庆娟,薄存菊,刘晓明,陈金生,卢振和,高崇荣..DSA引导下背根节脉冲射频治疗带状疱疹后神经痛的疗效及安全性[J].实用医学杂志,2012,28(13):2187-2190,4.基金项目
广东省医学科研基金(编号:A2011271) （编号:A2011271）
