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尖锐湿疣患者人乳头瘤病毒检测分型结果分析

王海清 杨云 张飞凤 徐延香 周剑峰

实用医学杂志2012,Vol.28Issue(13):2232-2234,3.
实用医学杂志2012,Vol.28Issue(13):2232-2234,3.DOI:10.3969/j.issn.1006-5725.2012.13.051

尖锐湿疣患者人乳头瘤病毒检测分型结果分析

Analysis on the genotyping results of HPV detection for 53 cases of condyloma acuminata patients

王海清 1杨云 1张飞凤 1徐延香 2周剑峰3

作者信息

  • 1. 336000,宜春学院医学院,宜春学院预防医学研究所
  • 2. 336200,江西省铜鼓县妇幼保健院
  • 3. 336200,江西省铜鼓县人民医院皮肤科
  • 折叠

摘要

Abstract

Objective To explore the subtype distribution and characteristics of the HPV types of condyloma acuminata (CA) in Yichun district, Jiangxi Province. Methods The object of study was patients from Tonggu and Fengxin county and Yuanzhou district of Yichun, Jiangxi. The HPV DNA detection and genotyping was done through GP-PCR and nucleotide sequencing. Results Among 53 cases of biopsy specimen of the wart tissue collected, 30 cases were Type 3 HPV DNA subtype, 15 cases of Type 11 (50.0%), 13 cases of Type 6 (43.3%) and 2 cases of Type 16 (6.7%). The total positive rate was 56.6% (30/53), and 93.3% of the cases, that is, 28 cases were low risk type (the Type 6/11). Conclusion The local CA patients are HPV unitary type infection. HPV 11, 6 is the majority and is the superior subtype of CA.

关键词

尖锐湿疣/HPV/基因分型

Key words

Condyloma acuminate/ Human papillomavirus/ Genotyping

引用本文复制引用

王海清,杨云,张飞凤,徐延香,周剑峰..尖锐湿疣患者人乳头瘤病毒检测分型结果分析[J].实用医学杂志,2012,28(13):2232-2234,3.

基金项目

中国癌症基金会-中国生殖器疣多中心临床流行病学研究项目(编号:MED-GEN03-07V1) (编号:MED-GEN03-07V1)

实用医学杂志

OA北大核心CSTPCD

1006-5725

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