新疆农业科学2012，Vol.49Issue(7)：1279-1283,5.DOI:10.6048/j.issn.1001-4330.2012.07.017
野山杏提取物对高脂血症大鼠脂代谢的影响
Effect of WAE on Lipid Metabolism in Hyperlipidemia Rats
摘要
Abstract
The purpose of this research was to investigate the effect of wild apricot extracts ( WAE) on lipid metabolism of hyperlipidemia rats. [ Method ] On the basis of establishing hyperlipidemia rat model, effect of WAE on the serum lipids level, the activities of ALT and AST in serum, lipid metabolite enzyme in liver,the activities of MDA, and pathology change of liver were investigated. [ Result] WAE could obviously decrease the content of TC, TG, LDL-C and the activities of ALT and AST and increase the content of HDL - C of serum in hyperlipidemia rats drenched with high fat suspension. WAE also lowered level of MDA in liver tissue. The degrees of hepatic steatosis in WAE groups were lighter than those in hyperlipidemia model group, especially in the high dose group, which was close to normal essentially. WAE plays an important role in enhancing the LPL and HL activity and inhibiting LPS. [ Conclusion ] WAE indeed had the function of reducing blood lipid of hyperlipidemia rats in addition to the counteraction atherosclerosis. To some extent, WAE also had good prevention to fatty deposition in liver. Moreover, treatment of WAE showed a certain relationship with dosage.关键词
野山杏提取物/高脂血症/脂代谢Key words
wild apricot extracts (WAE) / hyperlipidemia/ lipid metabolism分类
农业科技引用本文复制引用
阿依姑丽·艾合麦提,戴小华,帕尔哈提·柔孜,张华,王颖..野山杏提取物对高脂血症大鼠脂代谢的影响[J].新疆农业科学,2012,49(7):1279-1283,5.基金项目
新疆维吾尔自治区高校科研计划科学研究重点项目(XJEDU2009I12) （XJEDU2009I12）
