畜牧兽医学报2012，Vol.43Issue(8)：1186-1191,6.
济宁青山羊生后发育阶段GnRH与GnRHR阳性细胞在下丘脑分布规律的研究
Distribution Patterns of GnRH and GnRHR Positive Cells in Hypothalamus at Different Postnatal Stages in Jining Gray Goats
摘要
Abstract
In order to detect the morphological changes and distribution patterns of GnRH and GnRHR in hypothalamus at different postnatal stages in Jining Gray goats, immunohistochemical Strept Avidin Biotin-Peroxidase Complex (SABC) three-step method was used to study the distribution of GnRH and GnRHR in hypothalamus in goats at 0, 2, 4 and 6 months old. The results showed that GnRH and GnRHR positive cells were widely scattered in hypothalamus. Most of the positive cells were distributed in medial preoptic area (MPA), mamillary nucleus (MB), supraoptic nucleus (SON) and suprachiasmatic nucleus (SCN). The size and number of positive cells were increased with the increase of month old. The numbers of positive GnRH and GnRHR cells were significantly higher at 2 month old (puberty) than that at birth. The results suggest that GnRH and GnRHR secreted by hypothalamus might play a pivotal role in the onset of puberty and the maintenance of maturation in Jining Gray goat at the postnatal developing stage.关键词
济宁青山羊/GnRH/GnRHR/下丘脑/免疫组织化学Key words
Jining Gray goat/ GnRH/ GnRHR/ hypothalamus/ immunohistochemistry分类
农业科技引用本文复制引用
刘宵,王树迎,尹玉涛,张德敏,黄丽波,侯衍猛..济宁青山羊生后发育阶段GnRH与GnRHR阳性细胞在下丘脑分布规律的研究[J].畜牧兽医学报,2012,43(8):1186-1191,6.基金项目
国家自然科学基金项目(30871832) （30871832）
山东省自然科学基金(ZR2009DM027) （ZR2009DM027）
