新医学2012，Vol.43Issue(10)：729-731,3.DOI:10.3969/g.issn.0253-9802.2012.10.013
糖化血清蛋白与胎儿发育及代谢轴关系的研究
Study on the relationship between glycosylated serum protein with the intrauterine fetal growth and metabolism axis
摘要
Abstract
Objective: To study the Correlation between GSP and intrauterine fetal growth, metabolism axis by comparing the GSP concentration of small for gestational age (SGA) and appropriate for gestational age( AGA). Methods: Twenty-five cases of SGA and 35 cases of AGA were enrolled, and the latter as normal control group. The cord blood level of GSP, insulin and IGF-1 as well as the birth weight and length, head circumference and BMI were measued. Results: GSP, insulin and IGF-1 concentration of SGA was lower than those of AGA ( P < 0. 05). GSP concentration was positively related to birth weight, birth length, head circumference, body mass index (BMI) , all P <0. 05. Conclusions: SGA has lower level of GSP, insulin, IGF-1 than AGA, indicating that SGA should have lower intrauterine blood glucose. GSP could reflect the intrauterine fetal development and nutritional status.关键词
糖化血清蛋白/小于胎龄儿/胰岛素/胰岛素样生长因子-1Key words
Glycosylated serum protein/ Small for gestational age/ Insulin/ Insulinlike growth factor 1引用本文复制引用
郭蕾,肖作源,李志标,唐新意,张雪华..糖化血清蛋白与胎儿发育及代谢轴关系的研究[J].新医学,2012,43(10):729-731,3.基金项目
广东省科技计划项目(2003B30505) （2003B30505）
