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快中子诱发U251神经胶质瘤细胞的生物效应研究

杨磊 王潇 孔福全 隋丽 崔素珍 郑洁莹 马南茹 赵葵

中国工程科学2012,Vol.14Issue(8):91-95,5.
中国工程科学2012,Vol.14Issue(8):91-95,5.

快中子诱发U251神经胶质瘤细胞的生物效应研究

A biological effectiveness study on U251 induced by fast neutrons

杨磊 1王潇 1孔福全 1隋丽 1崔素珍 1郑洁莹 1马南茹 1赵葵1

作者信息

  • 1. 中国原子能科学研究院,北京102413
  • 折叠

摘要

Abstract

Objective: U251 cells were exposed to fast neutrons of 14 MeV energy, and dose-response relationships were derived; Methods; cell samples were exposed to fast neutrons. Radiation doses were 1 Gy, 3 Gy, 5 Gy and 7 Gy respectively. The cell survival, apoptotic rate and proliferation were tested after irradiation; Result: with the growth of the radiation dose, cell survival was declined, and apoptotic rate was promoted; the speed of the cell proliferation, which was observed 48 h after irradiation, was slowed down obviously; Conclusion: compared to 晊 ray, fast neutrons have higher relative biological effectiveness.

关键词

快中子/U251细胞/生物效应/剂量效应曲线

Key words

fast neutron/U251 cell/biological effectiveness/dose-respond curve

分类

医药卫生

引用本文复制引用

杨磊,王潇,孔福全,隋丽,崔素珍,郑洁莹,马南茹,赵葵..快中子诱发U251神经胶质瘤细胞的生物效应研究[J].中国工程科学,2012,14(8):91-95,5.

基金项目

国家自然科学基金项目(11079054) (11079054)

中国工程科学

OA北大核心CSTPCD

1009-1742

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