中国全科医学2012，Vol.15Issue(25)：2882-2883,2.DOI:10.3969/j.issn.1007-9572.2012.09.009
诊断多发性硬化的两种McDonald标准的比较研究
Comparative Study on Two McDonald Criteria for Diagnosis of Multiple Sclerosis
摘要
Abstract
Objective To compare the revised diagnostic criteria of multiple sclerosis ( MS ) proposed by McDonald et al in 2005 and 2011 so as to know the sensibility of the two diagnosis criteria. Methods Totally 78 patients with clinical features suggestive of MS were chosen and they were then diagnosed by the two diagnostic criteria. Then the Fisher's exact test was used for comparison. Results According to 2005 -revised McDonald criteria, 51 patients ( 65.4% ) were diagnosed as having MS and 27 ( 34. 6% ) as possibly having MS; while according to 2010 - rivesed McDonald criteria the numbers were respectively 57 ( 73. 1% ) and 21 ( 26. 9% ), with no significant difference ( P > 0. 05 ). Conclusion The 2010 - revised McDonald criteria has slightly higher sensitivity compared with the 2005 - revised, which is mainly due to the simplification of MRI criteria demonstrating dissemination of lesions in time, suggesting a potential clinical feasibility of the 2010 revision.关键词
多发性硬化/McDonald标准/诊断Key words
Multiple sclerosis/ McDonald criteria/ Diagnosis分类
医药卫生引用本文复制引用
刘广志,何洋,杨亭亭,高旭光,许贤豪..诊断多发性硬化的两种McDonald标准的比较研究[J].中国全科医学,2012,15(25):2882-2883,2.基金项目
国家自然科学基金资助项目(81171123) （81171123）
