摘要
Abstract
Objective Ischemic colitis is easy to be misdiagnosed due to its unobvious early clinical symptoms. Selective arteriography of inferior mesenteric artery is the gold standard for ischemic colitis but is very expensive. This study aims to investigate the diagnostic value of plasma D-dimer test for ischemic colitis in order to find a simple, economical and sensitive diagnosis method. Methods 39 suspected cases of ischemic colitis admitted to our hospital from June 2009 to June 2011 were drew blood 24 h within the attack of abdominal pain to test D-dimer, and then were confirmed by selective arteriography of inferior mesenteric artery. Statistical software of Prism 3. 0 was used to analyze the diagnostic value of D-dimer test for ischemic colitis. Results According to the results of D-dimer, 28 cases were diagnosed as ischemic colitis and their average D-dimer level was (1. 70 ±0. 10) mg/L 11 cases were diagnosed as non-ischemic colitis and their average D-dimer level was (0. 18 ±0. 02) mg/L The difference of the D-dimer level between the two groups was statistically significant (t = 49. 6378, P<0. 05) . According to the results of selective arteriography of inferior mesenteric artery, 30 cases were confirmed as ischemic colitis and 9 cases were confirmed as non-ischemic colitis. The sensitivity, specificity and positive likelihood ratio of D-dimer test for the diagnosis of ischemic colitis were 86. 67% , 77. 78% and 3. 90 respectively. Conclusion D-dimer test, with high sensitivity and specificity, has good diagnostic value in the diagnosis of ischemic colitis, and it is also simple and economical, deserving to be promoted in clinic. During diagnosis, the disease history of the patients should be inquired in detail to comprehensively analyze the disease assisted by auxiliary examination. Suspected cases should be given selective arteriography of inferior mesenteric artery or colonoscopy timely to confirm diagnosis.关键词
结肠炎,缺血性/D-二聚体/诊断Key words
Colitis, ischemic/ D-dimer/ Diagnosis分类
医药卫生
