首页|期刊导航|中国神经再生研究（英文版）|Stress and strain analysis on the anastomosis site sutured with either epineurial or perineurial sutures after simulation of sciatic nerve injury
中国神经再生研究（英文版）2012，Vol.7Issue(29)：2299-2304,6.DOI:10.3969/j.issn.1673-5374.2012.29.009
Stress and strain analysis on the anastomosis site sutured with either epineurial or perineurial sutures after simulation of sciatic nerve injury
Stress and strain analysis on the anastomosis site sutured with either epineurial or perineurial sutures after simulation of sciatic nerve injury
摘要
Abstract
The magnitude of tensile stress and tensile strain at an anastomosis site under physiological stress is an important factor for the success of anastomosis following suturing in peripheral nerve injury treatment.Sciatic nerves from fresh adult cadavers were used to create models of sciatic nerve injury.The denervated specimens underwent epineurial and perineurial suturing.The elastic modulus (40.96 ± 2.59 MPa) and Poisson ratio (0.37 ± 0.02) of the normal sciatic nerve were measured by strain electrical measurement.A resistance strain gauge was pasted on the front,back,left,and right of the edge of the anastomosis site after suturing.Strain electrical measurement results showed that the stress and strain values of the sciatic nerve following perineurial suturing were lower than those following epineurial suturing.Scanning electron microscopy revealed that the sciatic nerve fibers were disordered following epineurial compared with perineurial suturing.These results indicate that the effect of perineurial suturing in sciatic nerve injury repair is better than that of epineurial suturing.关键词
sciatic nerve injury/epineurial suture/perineurial suture/strain electrical measurement/anastomosis site/tensile stress/tensile strain/elastic modulus/Poisson ratio/biomechanics/peripheral nerve injury/neural regenerationKey words
sciatic nerve injury/epineurial suture/perineurial suture/strain electrical measurement/anastomosis site/tensile stress/tensile strain/elastic modulus/Poisson ratio/biomechanics/peripheral nerve injury/neural regeneration引用本文复制引用
Guangyao Liu,Qiao Zhang,Yan Jin,Zhongli Gao..Stress and strain analysis on the anastomosis site sutured with either epineurial or perineurial sutures after simulation of sciatic nerve injury[J].中国神经再生研究（英文版）,2012,7(29):2299-2304,6.基金项目
This project was funded by the Key Project of Clinical Specialty of Ministry of Public Health,No.2007-353. （）
