中国比较医学杂志2012,Vol.22Issue(7):32-35,4.DOI:10.3969.j.issn.1671.7856.2012.007.009
正常猕猴与人的视网膜电图比较
The Comparation of the Electroretinogram (ERG) between Normal Rhesus Monkeys and Humans
夏峰 1安晶 1张磊 1刘锐 1张作明1
作者信息
- 1. 第四军医大学航空航天医学系航临教研室,西安710032
- 折叠
摘要
Abstract
Objective To compare the difference between the electroretinogram (ERG) normal rhesus monkeys and humans, and provide a base for further study on the application of rhesus monkey retinal disease as an experiment model. Methods The electroretnogram (ERG) was recorded in 7 normal rhesus monkey (14 eyes) and 8 human (16 eyes). The recording items of ERG included rod response b wave, cone response, max response a and b waves, oscillatory potential 02, 30Hz flicker ERG 2P. The results were statistically tested. Results The ERG waveform results in rhesus monkey are similar to those in humans, but the amplitudes were decreased and the implicit times were prolonged compared with the humans, and the differences in the amplitude of the Cone ERG and the flicker ERG were not statistically significant. Conclusions The retinal function in rhesus monkey is quite similar to those in humans in the ERG recording. Rhesus monkey is a good animal model for the study on human retinal disease especially the macular.关键词
猕猴/视网膜电图/眼底功能Key words
Rhesus monkeys/ ERG/ Fundus function分类
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夏峰,安晶,张磊,刘锐,张作明..正常猕猴与人的视网膜电图比较[J].中国比较医学杂志,2012,22(7):32-35,4.