中国比较医学杂志2012,Vol.22Issue(7):72-75,4.DOI:10.3969.j.issn.1671.7856.2012.007.018
人源化鼠嵌合肝动物模型研究进展
Research Progression of Establishment of Animal model of Tolerant Rats with Chimeric Human Liver
李瑞生 1李晓娟 1沈宏辉 1郭立新2
作者信息
- 1. 解放军第302医院实验技术研究保障中心,北京100039
- 2. 北京大学首钢医院内分泌科,北京1000144
- 折叠
摘要
Abstract
Animal model is an important instrument for human diseases research, pathogenesis, medicine research. At present, liver diseases still damage human healthy seriously because there are no proper animal models to effectively reflect procedures of human diseases. Therefore establishment of animal model of tolerant rats with chimeric human liver will have extensive application prospects for pathogenesis of human liver diseases, vaccine and medicine exploitation and treatment of human liver diseases.关键词
鼠嵌合肝/肝细胞移植/干细胞移植/模型,动物Key words
Mice chimeric liver/Hepatocyte transplantation/Stem cell transplantation/Model,animal分类
医药卫生引用本文复制引用
李瑞生,李晓娟,沈宏辉,郭立新..人源化鼠嵌合肝动物模型研究进展[J].中国比较医学杂志,2012,22(7):72-75,4.