中国比较医学杂志2012，Vol.22Issue(8)：74-80,7.DOI:10.3969.j.issn.1671.7856.2012.008.017
特发性肺纤维化发病机制的研究进展
Advances in Research of Pathogenesis of Idiopathic Pulmonary Fibrosis
摘要
Abstract
Idiopathic pulmonary fibrosis is one of a group of chronic interstitial lung diseases of unknown causes, and is characterized by alveolar epithelial cell injury, abnormal proliferation of fibroblasts and excessive deposition of extracellular matrix. There are limited therapeutic options, poor prognosis, low long-term survival rate and is associated with increasing incidence since the pathogenic mechanisms are elusive. This demands a better understanding of the molecular mechanisms underlying the pathogenesis. It is most essential to know the onset and progression of this disease, especially in relevance to human health. In this paper, we reviewed the advances in research of idiopathic pulmonary fibrosis.关键词
特发性肺纤维化/炎症反应/上皮细胞/成纤维细胞/机制Key words
Idiopathic pulmonary fibrosis/ Inflammation/ Epithelial cells/ Fibroblast/ Mechanisms分类
医药卫生引用本文复制引用
孔勤,陈民利..特发性肺纤维化发病机制的研究进展[J].中国比较医学杂志,2012,22(8):74-80,7.基金项目
浙江省科技专项(2006C17019) （2006C17019）
浙江省卫生高层次创新人才培养工程项目. （）
