中国真菌学杂志2012，Vol.7Issue(3)：146-149,4.
肺泡巨噬细胞表面甘露糖受体在免疫抑制大鼠肺隐球菌感染中的实验研究
Effect of mannose receptor of alveolar macrophage on cryptococcal pneumonia in immunodepressive rats
摘要
Abstract
Objective To explore the effect of mannose receptor of alveolar macrophage on cryptococcal pneumonia in immunodepressive rats. Methods Immunodepressive rats model was set up to observe the influence of immunodepression on the expression of mannose receptors by flow cytometry. The alveolar macrophages were cocultured with Cryptococcus neoformans and the phagocytosis was observered. Results On the endpoint of the observation, the expression of mannose receptors and the phagotosis of Cryptococcus neoformans in immunodepressive rats showed no significant difference with those in normal rats. Conclusions Immunodeficiency is not the key factor for the expression of mannose receptors.关键词
肺泡巨噬细胞/甘露糖受体/隐球菌/免疫抑制Key words
alveolar macrophage/mannose receptor/ Cryptococcus neoformans /immunosuppression分类
医药卫生引用本文复制引用
徐楠,肖琴,姚玮,储伟芳,肖晓庆,顾菊林,温海..肺泡巨噬细胞表面甘露糖受体在免疫抑制大鼠肺隐球菌感染中的实验研究[J].中国真菌学杂志,2012,7(3):146-149,4.基金项目
国家自然科学基金(30972817) （30972817）
