中国真菌学杂志2012，Vol.7Issue(4)：214-218,5.
自身免疫性大疱病合并侵袭性肺曲霉病:3例报告
Invasive pulmonary aspergillosis in autoimmune bullous diseases patients:three cases report
摘要
Abstract
Objective To study the diagnosis and treatment of invasive pulmonary aspergillosis in autoimmune bullous diseases patients under long-term glucocorticoids treatment by retrospectively reviewing three cases. Methods Report three cases of autoimmune bulious diseases with invasive pulmonary aspergillosis. KOH smear and culture, antigen detection, chest CT scan and his-topathologic test were used to diagnose the patients. The organisms isolated from the sputum were identified as Aspergillus fumigatus A. Flavus and Emericella echinulata by morphological and molecular methods. Results Three cases were diagnosed as invasive pulmonary aspergillosis. The patients were cured with voriconazole treatment and other antifungal agents. Conclusion Autoimmune bullous diseases patients should be watched out emerging invasive apergillosis during long-term glucocorticoids therapy. Combined laboratory examinations will be helpful in early diagnosis and increasing efficacy.关键词
自身免疫性大疱病/糖皮质激素/肺曲霉病Key words
autoimmune bullous diseases/glucocorticoids/invasive pulmonary aspergillosis分类
医药卫生引用本文复制引用
余进,牟向东,万喆,阙呈立,李若瑜..自身免疫性大疱病合并侵袭性肺曲霉病:3例报告[J].中国真菌学杂志,2012,7(4):214-218,5.基金项目
卫生部部属(管)医院2010-2012年度临床学科重点项目基金(2010-2012),艾滋病和病毒性肝炎等重大传染病防治科技重大专项资助课题(2008ZX1004-002) （管）
