中华医学杂志（英文版）2012，Vol.125Issue(16)：2925-2928,4.DOI:10.3760/cma.j.issn.0366-6999.2012.16.023
Photodynamic therapy of condyloma acuminata in pregnant women
Photodynamic therapy of condyloma acuminata in pregnant women
YANG Yu-guang 1ZOU Xian-biao 2ZHAO Hua 1ZHANG Yun-jie 2LI Heng-jin1
作者信息
- 1. Department of Dermatology, Chinese People's Liberation Army General Hospital, Beijing 100853, China
- 2. Department of Dermatology, First Affiliated Hospital of Chinese People's Liberation Army General Hospital, Beijing 100048, China
- 折叠
摘要
Abstract
Background Photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA) is an emerging technique for the treatment of genital human papillomavirus (HPV)-induced benign and premalignant lesions.We report here in a case series of condyloma acuminata (CA) in pregnancy successfully treated with ALA-PDT.Methods Five pregnant patients with CA received three to four times treatment respectively.Patients were followed up for 6-23 months after treatment.Results The clearance rate of genital warts was 100％.No recurrence was found during the follow-up period.Major adverse events reported were mild erosion,pain,and local edema.All pregnancies resulted in healthy live births without delivery complications.Conclusions PDT with topical ALA seems to be safe and effective in the treatment of CA in pregnancy.It demonstrated high clearance rate of warts,was well-tolerated by patients,and showed no adverse effects on mothers or fetuses.ALA-PDT may be an ideal strategy of treatment for pregnant women with CA.关键词
Condyloma acuminatum/pregnancy/aminolevulinic acid/photodynamic therapyKey words
Condyloma acuminatum/pregnancy/aminolevulinic acid/photodynamic therapy引用本文复制引用
YANG Yu-guang,ZOU Xian-biao,ZHAO Hua,ZHANG Yun-jie,LI Heng-jin..Photodynamic therapy of condyloma acuminata in pregnant women[J].中华医学杂志（英文版）,2012,125(16):2925-2928,4.
