癌变·畸变·突变2012，Vol.24Issue(5)：376-378,382,4.DOI:10.3969/j.issn.1004-616x.2012.05.014
胃肠道恶性肿瘤患者血清AFP、CEA和CA19-9的表达特征探讨
Expression characteristics of serum AFP, CEA and CA19-9 in patients with gastrointestinal malignant tumors
摘要
Abstract
OBJECTIVE: To explore expression characteristics of serum tumor markers AFP, CEA, CA19-9 in patients with the gastrointestinal malignant tumors. METHODS: Expression levels of AFP, CEA, CA19-9 in serum of 126 patients with gastrointestinal cancers were analyzed by Roche automatic electrochemical luminescence, and the relationship of these markers with clinicopathological factors were studied. RESULTS: Serum CEA expression increased with the depth of tumor invasion, clinical stage, and distant metastasis, the difference was statistically significant (P<0.05). Serum CA19-9 expression levels increased significantly with clinical stage, and distant metastasis difference (P<0.05). Serum level of AFP expression was not significantly different between the various clinical pathological factors. CONCLUSION: Expression levels of serum CEA, CA19-9 were closely related to the clinical condition of patients with gastrointestinal cancers.关键词
AFP/CEA/CA19-9/胃肠道恶性肿瘤/肿瘤标志物Key words
AFP/ CEA/ CA19-9/ gastrointestinal tumors/ tumor markers分类
医药卫生引用本文复制引用
黄素英,黄昌明,田俊,陈华..胃肠道恶性肿瘤患者血清AFP、CEA和CA19-9的表达特征探讨[J].癌变·畸变·突变,2012,24(5):376-378,382,4.基金项目
福建省教育厅科技项目(JB06224) （JB06224）
福建医科大学教授基金(JS060018) （JS060018）
