癌变·畸变·突变2012，Vol.24Issue(5)：383-385,388,4.DOI:10.3969/j.issn.1004-616x.2012.05.016
马尾松松针粉袋泡茶水提物的急性毒性和致突变性研究
Acute toxicity and mutagenicity tests of aqueous extract of masson pine needle powder teabags
摘要
Abstract
OBJECTIVE: To study the acute toxicity and mutagenicity of aqueous extract of masson pine powder teabags. METHODS: Acute toxicity tests were done in mice and rats. Ames test, micronucleus test and sperm abnormality test were used to examine the acute toxicity and mutagenicity of aqueous extract of masson pine powder teabags. RESULTS: The of aqueous extract of masson pine needle powder teabags in mice and rats were both more than 240.0 g/kg. No statistical difference in revertant colonies was found in the Ames test with and without S9. The micronucleus rates and sperm abnormality rates in all doses showed no significant difference from the negative control. CONCLUSION: Aqueous extract of masson pine needle powder teabags showed no acute toxicity and mutagenicity under these test conditions.关键词
马尾松松针粉/袋泡茶/急性毒性/Ames试验/微核试验/精子畸形试验Key words
masson pine needle powder/ teabags/ acute toxicity/ Ames test/ micronucleus test/ sperm abnormality test分类
医药卫生引用本文复制引用
刘臻,王茵,梅松,刘冬英,来伟旗,傅颖,陈建国,马洁桃,么春艳,张岭..马尾松松针粉袋泡茶水提物的急性毒性和致突变性研究[J].癌变·畸变·突变,2012,24(5):383-385,388,4.基金项目
浙江省科技计划项目(2009F20035、2009R50028),浙江省卫生高层次创新人才培养项目,浙江省医学支撑学科营养学(11-zc03) （2009F20035、2009R50028）
