重庆医学2012，Vol.41Issue(29)：3017-3019,3022,4.DOI:10.3969/j.issn.1671-8348.2012.29.001
支气管肺发育不良婴儿肺功能的初步研究
The lung function tests of infants with bronchopulmonary dysplasia by ultrasonic flow meter
摘要
Abstract
Objective To investigate lung function characteristics of preterm infants with and without bronchopulmonary dyspla-sia(BPD) , and to assess the influence of premature birth and BPD for the functional development of the lungs. Methods Twenty-two preterm infants with BPD,25 preterm infants without BPD and 34 healthy born-infants were studied at a matched post menstrual age of 38 weeks(37 weeks to 41 weeks) during quiet natural sleep. Lung function parameters measured were functional residual capacity(FRC/kg) and ventilation inhomogeneity by multiple breath washout measurements using an ultrasonic flow meter, as well as tidal breathing parameters. Results Compared with healthy term infants, preterm infants with BPD and preterm infants without BPD had lower FRC/kg, increased ventilation inhomogeneity, expressed as LCI, higher respiratory rates and lower ratios of time to peak expiratory flow and expiratory time(TPTEF/TE)(P<0. 01). The BPD infants differed from preterm infants without BPD in the same variables(P<0. 05). Conclusion At the same postmenstrual age of 38 weeks,BPD and non-BPD preterm have a significant reduced FRC,impairment of gas mixing efficiency and small airway obstruction,the BPD group is more evident.关键词
支气管肺发育不良/呼吸功能试验/婴儿Key words
bronchopulmonary dysplasia/respiratory function tests/infant引用本文复制引用
陈泽伟,余加林,刘晓红,李腾..支气管肺发育不良婴儿肺功能的初步研究[J].重庆医学,2012,41(29):3017-3019,3022,4.基金项目
深圳市医疗重点学科专项建设基金资助项目(2001B19). （2001B19）
