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热毒宁注射液与常用输液及其他药物配伍后的变化

韦曦 欧阳小琳 许盈 卓思珺 卢荣全

儿科药学杂志2012,Vol.18Issue(9):27-30,4.
儿科药学杂志2012,Vol.18Issue(9):27-30,4.

热毒宁注射液与常用输液及其他药物配伍后的变化

Compatibility and Stability of Reduning Infusion Mixtures

韦曦 1欧阳小琳 1许盈 1卓思珺 1卢荣全2

作者信息

  • 1. 广西柳州市人民医院,广西柳州545006
  • 2. 桂林医学院药学院,广西桂林541004
  • 折叠

摘要

Abstract

Objective: To study the compatibility of Reduning injection with common medicines. Methods: In accordance with the method described in China's pharmacopoeia 2010 edition, the pH, insoluble particle, and the changes of spectral absorption after combination were assayed. Results: Reduning injection became dark, the spectral absorption curve changed, and chlorogenic acid decomposed which was a active substance when mixed with high pH injection such as injections containing sodium bicarbonate, amoxicillim/sulbactam sodium and dexamethasone sodium phosphate. Conclusions: Reduning injection should be diluted by 0. 9% sodium chloride injection and applied intravenous infusion. Medicine combination of reduning injection and high pH medicines should be applied through separate injection or flushed perfusion tube.

关键词

热毒宁注射液/配伍/pH值

Key words

Reduning injection/Compability of medicines/pH

分类

医药卫生

引用本文复制引用

韦曦,欧阳小琳,许盈,卓思珺,卢荣全..热毒宁注射液与常用输液及其他药物配伍后的变化[J].儿科药学杂志,2012,18(9):27-30,4.

儿科药学杂志

OACSTPCD

1672-108X

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