分析测试学报2012，Vol.31Issue(10)：1266-1271,6.DOI:10.3969/j.issn.1004-4957.2012.10.009
液相色谱-串联质谱法测定蔬菜、水果中5种阿维菌素类药物残留量
Determination of 5 Avermectin Residues in Fruits and Vegetables by Liquid Chromatography-Tandem Mass Spectrometry
摘要
Abstract
A liquid chromatography - tandem mass spectrometric method was developed for the simultaneous determination of 5 avermectin residues ( e. g. abamectin, ivermectine, eprinomectin, emamectin benzoate Bla and emamectin benzoate Blb) in fruits and vegetables. After extracted with acetonitrile, avermectin residues were cleaned up by PSA and C18 dispersive solid phase extraction. Influences of mobile phases, procedure of solvent gradient and temperature of the desolvation gas were investigated. Experimental results revealed that the most signal intense precursor ions( [ M + NH4 ] + ) were observed when desolvation gas temperature of 250 ℃ was used. The method was evaluated in terms of the limits of detection and quantitation. The linearity of the analytical response within the studied range of 3 orders of magnitude was excellent, with correlation coefficients higher than 0. 999. The mean recoveries of all analytes in 5 spiked fruits and vegetables matrix were in the range of 74% - 110% , with relative standard deviations of 0.4% -12.1%. The limits of detection for abamectin, ivermectine, eprinomectin, emamectin benzoate Bla and emamectin benzoate Bib were 0.6, 0.6, 0.3, 0.06, 0.6 μg/kg, respectively. The method was efficient, reliable and sensitive, and could meet the requirements for the determination of 5 avermectin residues in fruits and vegetables.关键词
液相色谱-串联质谱/阿维菌素类药物残留/蔬菜/水果Key words
liquid chromatography - tandem mass spectrometry ( LC - MS/MS) / avermectin residues/ fruits/ vegetables分类
化学化工引用本文复制引用
赵肖华,曹赵云,牟仁祥,许萍,陈铭学..液相色谱-串联质谱法测定蔬菜、水果中5种阿维菌素类药物残留量[J].分析测试学报,2012,31(10):1266-1271,6.基金项目
浙江省科技计划项目(2011C37053) （2011C37053）
