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芦丁铬(Ⅲ)配合物的合成、表征及其抗氧化活性研究

杨武群 吕华冲 蔡金艳 高奥 周鹏飞 王平 王健壮

广东药学院学报2012,Vol.28Issue(5):493-496,4.
广东药学院学报2012,Vol.28Issue(5):493-496,4.DOI:10.3969/j.issn.1006-8783.2012.05.007

芦丁铬(Ⅲ)配合物的合成、表征及其抗氧化活性研究

The synthesis, characterization and antioxidant properties of rutin-chromium (Ⅲ) complexes

杨武群 1吕华冲 1蔡金艳 1高奥 1周鹏飞 1王平 1王健壮1

作者信息

  • 1. 广东药学院药科学院,广东广州510006
  • 折叠

摘要

Abstract

Objective To synthetize and characterize rutin-chromium (Ⅲ) complexes, and detect its antioxidation activities. Methods Rutin was taken as a lead compound, synthesized with trace element chromium and obtained rutin-chromium ( Ⅲ ) complexes. The complexes were confirmed by IR, UV-Vis, elemental analysis, thermo gravimetric analysis and atomic absorption spectrometric. Meanwhile, the antioxidation activities were investigated by hydroxyl radicals ( · OH) and superoxide radicals ( O2-· ). Results and Conclusion The molar ratio between rutin and chromium is 1: 1. The structural formula is inferred as CrCl2C27 H32 O18 · 7H2O. The antioxidation activities results demonstrate that rutin-chromium ( Ⅲ) complexes is stronger than rutin on the antioxidation activities.

关键词

芦丁//金属配合物/氧自由基

Key words

rutin/ chromium/ metal complexes/ oxygen free radicals

分类

医药卫生

引用本文复制引用

杨武群,吕华冲,蔡金艳,高奥,周鹏飞,王平,王健壮..芦丁铬(Ⅲ)配合物的合成、表征及其抗氧化活性研究[J].广东药学院学报,2012,28(5):493-496,4.

广东药学院学报

OACSTPCD

1006-8783

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