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均匀设计法优化马缨丹提取工艺研究

尹永芹 严优芍 崔红花 沈志滨 谢浚明

广东药学院学报2012,Vol.28Issue(5):506-509,4.
广东药学院学报2012,Vol.28Issue(5):506-509,4.DOI:10.3969/j.issn.1006-8783.2012.05.010

均匀设计法优化马缨丹提取工艺研究

Uniform design method for optimizing the extraction technology of Lantana Camara

尹永芹 1严优芍 1崔红花 1沈志滨 1谢浚明1

作者信息

  • 1. 广东药学院中药学院,广东广州510006
  • 折叠

摘要

Abstract

Objective To optimize the extraction process of flavonoids from Lantana camara. Methods The total flavonoids from L. camara were determined to obtain the best conditions by uniform design test, using soxhlet extraction method with rutin as reference at 406 nm wavelength. Results The uniform design experiments resulted the optimal process as follows: the extraction with 90% ethanol for 4 hours, the solid-liquid ratio of 1 : 60, and particle degree of 24 mesh by soxhlet extractor. Conclusion The optimized technology is feasible with good repeatability.

关键词

马缨丹/总黄酮/均匀设计法/工艺优化

Key words

Lantana Camara/ total flavonoids/ uniform design method/ optimizing technology

分类

医药卫生

引用本文复制引用

尹永芹,严优芍,崔红花,沈志滨,谢浚明..均匀设计法优化马缨丹提取工艺研究[J].广东药学院学报,2012,28(5):506-509,4.

基金项目

国家自然科学基金项目(81202885) (81202885)

科技部"十二五"重大新药创制项目(2011ZX09102-007-03) (2011ZX09102-007-03)

广东省科技厅科技计划重点专项(2011A030100013) (2011A030100013)

广东省科技厅科技计划项目(2010B030700044) (2010B030700044)

2010年广东省教育厅高层次人才资助项目 ()

广东药学院学报

OACSTPCD

1006-8783

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