光学精密工程2012，Vol.20Issue(11)：2365-2372,8.DOI:10.3788/OPE.20122011.2365
用于阵列样品检测的扫描式表面等离子体共振生物传感器
Scanning surface plasmon resonance biosensor for array sample detection
摘要
Abstract
An scanning surface plasmon resonance biosensor was constructed to quantitatively detect array samples. First, based on the optimal rotation position in plane prism-coupling mode and a double-prism detection optical path, the scanning surface plasmon resonance biosensor for array sampleswas constructed. Then, the sample density of array samples was calculated. Finally, by taking the distilled water and glucose solution with different concentrations in 5, 10, 15, 20, 25, 30 and 35 mg/ mL as array samples to be measured, the multi-sample spots were detected by surface plasmon resonance method. Experimental results show that the resonance angles of array samples are 73. 745, 73. 919, 74. 052, 74. 185, 74. 306, 74. 408, 74. 549 and 74. 660? respectively, and the solution concentrations and their resonance angles show a good linear relation, which proves that the proposed method and device are feasibility. The device is significant for increasing the sample density of array samples and realizing the high precision detection.关键词
表面等离子体共振/生物传感器/阵列扫描/样品密度Key words
surface plasmon resonance/ biosensor/ array scanning/ sample density分类
信息技术与安全科学引用本文复制引用
齐攀,李莹,冯明创,钟金钢..用于阵列样品检测的扫描式表面等离子体共振生物传感器[J].光学精密工程,2012,20(11):2365-2372,8.基金项目
海洋赤潮灾害立体监测技术与应用国家海洋局重点实验室资助项目(No.MATHAB20120208) （No.MATHAB20120208）
暨南大学优秀本科推免生科研创新培育计划资助项目 （）
粤港关键领域重点突破招标资助项目(No.2005A20501001) （No.2005A20501001）
