广西医学2012，Vol.34Issue(11)：1444-1446,3.
红花多糖对人胃癌SGC-7901细胞抑制作用的初步研究
The Pilot Study on the Inhibition of Safflower Polysaccharideto Human Gastric Carcinoma Cell Line SGC-7901
摘要
Abstract
Objective To observe the effeet of Safftower potysaccharide( SPS ) on the eett protiferation and apoptosis of human gastric eareinoma eett tine SGC-7901. Methods SGC-7901 eetts were proeessed with different. eoneentrations of SPS during the same period. The morphotogy ehanges and pmtiferation of SGC-7901 eetts were observed wiht inverted miemseope. The apoplosis of SGC-7901 cott was detected by acridine orange(AO ) assay. Resutts SGC-7901 eetts in SPS group showed bad refraction,shrink,and more dead eetts in culture medium were observed. Resulls of AO ftuoreseent staining showed part of SGC-7901 eetts of eytoptasm condensed,chromatin increased,and the crescent-shaped shrinkage coutd be seen in some cetts nucteus. Conctusion SPS can markedty inhibit. the growth of SGC-7901 cetts and induce apoptosis of gastrie carcinoma cett tine SGC-7901 in vitro cukured in a time- and dose-dependent manner.关键词
红花多糖/SGC-7901细胞/细胞凋亡Key words
Safftower potysaeeharide/SGC-7901 cetts/Apoptosis分类
医药卫生引用本文复制引用
马新博,周振座,宫汝飞,石学魁,史琳,张安文,申海光,于声,王亚贤..红花多糖对人胃癌SGC-7901细胞抑制作用的初步研究[J].广西医学,2012,34(11):1444-1446,3.基金项目
广西教育厅科研项目(201204LX551) （201204LX551）
柳州医学高等专科学校科研项目(2011YB03) （2011YB03）
