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猪体内金黄色葡萄球菌及凝固酶阴性葡萄球菌耐药性调查及耐药基因分布研究

林大川 刘健华 王晶 孙娜 郭潇木 魏鸿堃 冯言言 曾振灵

华南农业大学学报2012,Vol.33Issue(4):550-555,6.
华南农业大学学报2012,Vol.33Issue(4):550-555,6.

猪体内金黄色葡萄球菌及凝固酶阴性葡萄球菌耐药性调查及耐药基因分布研究

Antimicrobial Resistance and Resistance Genes in Staphylococcus aureus and Coagulase-Negative Staphylococci Isolated from Swine

林大川 1刘健华 1王晶 1孙娜 1郭潇木 1魏鸿堃 1冯言言 1曾振灵1

作者信息

  • 1. 华南农业大学兽医学院,广东省兽药研制与安全评价重点实验室,广东广州510642
  • 折叠

摘要

Abstract

Ninety Staphylococcus strains, including 19 Staphylococcus aureus and 71 coagulase-negative Staphylococci, were isolated from different swine lymph node samples collected from Guangdong Province in 2010. Antimicrobial susceptibility testing was performed with agar dilution method according to the recommendations of the Clinical and Laboratory Standards Institute (CLSI). PCR detection was used to screen 13 resistance genes among these strains. Statistical methods were used to analyze the differences in resistance and the distribution of resistance genes in S. aureus and coagulase-negative Staphylococci. The results showed that resistance rates of S. aureus and coagulase-negative Staphylococci to macrolides, lin-cosamides, tetracycline were very high( > 80% ). There were no significant differences of antimicrobial resistance and the carriage rates of resistance genes between S. aureus and coagulase-negative Staphylococci , except that the coagulase-negative Staphylococci strains had a higher oxacillin resistance rate and higher limA and ermB gene carriage rates as compared with 5. aureus (P < 0. 05).

关键词

金黄色葡萄球菌/凝固酶阴性葡萄球菌/耐药性/耐药基因/

Key words

Staphylococcus aureus/coagulase-negative Staphylococci/resistance/resistance genes/swine

分类

农业科技

引用本文复制引用

林大川,刘健华,王晶,孙娜,郭潇木,魏鸿堃,冯言言,曾振灵..猪体内金黄色葡萄球菌及凝固酶阴性葡萄球菌耐药性调查及耐药基因分布研究[J].华南农业大学学报,2012,33(4):550-555,6.

基金项目

高等学校博士学科点专项科研基金(201044041100) (201044041100)

华南农业大学学报

OA北大核心CSCDCSTPCD

1001-411X

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