河南农业科学2012，Vol.41Issue(10)：14-18,5.
利用噬菌体随机肽库筛选抗原模拟表位的研究进展
A Review on Screening Mimicking Epitope of Antigen from Phage Random Peptide Library
摘要
Abstract
In this paper, the screening mimicking epitope of antigen from phage random peptide library was reviewed. The phage random peptide library is a technology by inserting the DNA sequences of polypeptide into the phage coat protein gene at the proper position and the heterolo-gous gene is expressed accompanied with the coat protein. Then,the displayed heterologous polypeptide can be kept relatively independent spatial structure and biological activity, which is a unity of genotype and phynotype. In recent years,phage random peptide library has been widely used for screening the mimicking epitope of various antigen and has made remarkable achievements.关键词
噬茵体随机肽库/噬菌体展示技术/模拟表位/抗原Key words
phage random peptide library/phage display technology/mimicking epitope/antigen分类
生物科学引用本文复制引用
裴亚峰,胡骁飞,王耀,侯玉泽,张改平,邓瑞广..利用噬菌体随机肽库筛选抗原模拟表位的研究进展[J].河南农业科学,2012,41(10):14-18,5.基金项目
农业部公益性行业(农业)科研专项(201203040) （农业）
河南省农业科学院科技发展及示范推广专项 （）
