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白花蛇舌草抑制Lewis肺癌小鼠自发转移的实验研究

李洁 李玉基 李博

中医药导报2012,Vol.18Issue(9):78-79,82,3.
中医药导报2012,Vol.18Issue(9):78-79,82,3.

白花蛇舌草抑制Lewis肺癌小鼠自发转移的实验研究

Experimental Research on Inhabitation Effect of Hedyotis Diffusa Willd on Lewis Lung Canser Spontaneous Metastasis in Mouse

李洁 1李玉基 2李博1

作者信息

  • 1. 山东中医药大学,山东济南250355
  • 2. 山东省药品不良反应监测中心,山东济南250013
  • 折叠

摘要

Abstract

Objective: To observe the effect of Hedyotis diffusa on inhibiting Lewis lung spontaneous metastasis in mouse. Methods: To establish the spontaneous metastasis model with subcutaneous injection Lewis lung cancer tumor cell suspension into the C57BL mouse through right axillaries and observe the changes of mouse's weight, solid tumor growth, lung metastasis, and immune organ index. Results: For the mice in Hedyotis diffusa role groups, the quality of mice' life obviously improved; the index of immune organs and the tumor inhibition rate were increased significantly, pulmonary metastasis nodules was significantly reduced compared with the blank group. Conclusion: Hedyotis diffusa has an inhibitory effect on Lewis lung cancer spontaneous metastasis.

关键词

白花蛇舌草/Lewis肺癌/抗肿瘤/自发转移

Key words

Hedyotis Diffusa Willd/ Lewis Lung Cancer/ Anti-tumor/ Spontaneous Metastasis

分类

医药卫生

引用本文复制引用

李洁,李玉基,李博..白花蛇舌草抑制Lewis肺癌小鼠自发转移的实验研究[J].中医药导报,2012,18(9):78-79,82,3.

基金项目

山东省自然科学基金课题(Y2008C24) (Y2008C24)

中医药导报

OACSTPCD

1672-951X

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