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黄芪防芷汤对变应性鼻炎患者血清IgE,IL-4,IL-12含量的影响

仲锡铜 张玲

实用临床医药杂志2012,Vol.16Issue(15):54-56,3.
实用临床医药杂志2012,Vol.16Issue(15):54-56,3.

黄芪防芷汤对变应性鼻炎患者血清IgE,IL-4,IL-12含量的影响

Influence of Astragalus Anti- Chih Tang on serum IgE,IL- 4, IL- 12 in patients with allergic rhinitis

仲锡铜 1张玲2

作者信息

  • 1. 山东大学附属省立医院药剂科,山东济南,250021
  • 2. 山东中医药大学药学院药物化学教研室,山东济南,250355
  • 折叠

摘要

Abstract

Objective To investigate the influence of Astragalus Anti - Chih Tang in patients with allergic rhinitisin. Methods Sixty - eight patients with allergic rhinitis were randomly divided into control group (n =34) and treatment group (n =34). The control group received budesonide,montelukast,and ketotifen. Based on the therapy of the control group,the treatment group received self - prescribed treatment. The serum levels of IgE,IL - 4 and IL - 12,allergic rhinitis symptom score and airway reactivity were observed before and after treatment. Results After treatment,the serum IgE,IL -4 levels in two groups were significantly lower (P<0.05). IL - 12 level was significantly higher (P< 0.05). IL-4 level in the treatment group was significantly lower than that in the control group (P<0. 05),and IL- 12 level was significantly higher than that in the control group ( P < 0.05). After treatment,the allergic rhinitis symptoms score in the treatment group was significantly lower than that in the control group (P<0. 05). The Fres,R5 and R20 in the treatment group were significantly lower (P<0. 05) and the treatment group decreased more significantly than the control group (P < 0. 05). Conclusion Astragalus Anti - Chih Tang has reliable efficacy in the treatment of allergic rhinitis. Its therapeutic effect may be related to Thl/Th2 which corrects the balance of the patient s body.

关键词

黄芪/防芷/变应性鼻炎/IgE/IL-4/IL-12

Key words

astragalus/anti-Chih/allergic rhinitis/IgE/IL-4/IL-12

分类

医药卫生

引用本文复制引用

仲锡铜,张玲..黄芪防芷汤对变应性鼻炎患者血清IgE,IL-4,IL-12含量的影响[J].实用临床医药杂志,2012,16(15):54-56,3.

基金项目

中国高校医学期刊临床专项资金(11220072) (11220072)

实用临床医药杂志

OACSTPCD

1672-2353

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