实用临床医药杂志2012，Vol.16Issue(15)：95-96,102,3.
异甘草酸镁预防急性白血病患者化疗药物性肝损害的疗效观察
Efficacy of magnesium isoglycyrrhizinate in prevention of chemotherapy drug- induced liver injury in patients with acute leukemia
徐茂忠 1徐昕 1赵钰 1秦如娟 1杨建刚1
作者信息
- 1. 江苏省江阴市人民医院血液科,江苏江阴,214400
- 折叠
摘要
Abstract
Objective To observe the efficacy of magnesium isoglycyrrhizinate in prevention of chemotherapy drug- induced liver injury in patients with acute leukemia. Methods Sixty - six patients with acute leukemia were randomly divided into prevention group ( n = 34) and control group (n = 32). The prevention group received chemotherapy drugs combined with magnesium isoglycyrrhizinate and the control group only received chemotherapy drugs. Results There was 15 cases (9. 6%) with liver injury in the prevention group,and 46 cases (31. 7%) in the control group. The difference between the two groups was statistically significant. The efficacy rate of liver injury prevention was 82. 7% in the prevention group,and 22.7% in the control group. There was significant difference between the two groups. Magnesium isoglycyrrhizinate - related adverse reactions in the course of treatment were not observed. Conclusion Magnesium isoglycyrrhizinate is effective in prevention of chemotherapy drug - induced liver injury in patients with acute leukemia. Thus it is worthy of promotion.关键词
异甘草酸镁/急性白血病/肝损害/疗效Key words
magnesium isoglycyrrhizinate/acute leukemia/liver injury/efficacy分类
医药卫生引用本文复制引用
徐茂忠,徐昕,赵钰,秦如娟,杨建刚..异甘草酸镁预防急性白血病患者化疗药物性肝损害的疗效观察[J].实用临床医药杂志,2012,16(15):95-96,102,3.
