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非小细胞肺癌患者血清中p53蛋白检测的临床意义

姚坚 陈金亮 陶一江 陈建荣

实用临床医药杂志2012,Vol.16Issue(17):43-45,3.
实用临床医药杂志2012,Vol.16Issue(17):43-45,3.

非小细胞肺癌患者血清中p53蛋白检测的临床意义

Clinical significance of measuring p53 protein in serum of patients with non-small cell lung cancer

姚坚 1陈金亮 1陶一江 1陈建荣1

作者信息

  • 1. 南通大学第二附属医院呼吸科,江苏南通,226001
  • 折叠

摘要

Abstract

Objective To investigate the clinical significance of p53 protein in serum patients with non-small cell lung cancer (NSCLC). Methods Serum samples of NSCLC patients and the group of healthy people were collected as well. p53 protein was determined with non-equilibrium radioimmunoassay method. Results Protein p53 levels in serum of NSCLC group (pre-operation) were higher than NSCLC group (post-operation). Protein p53 levels in serum of valid of chems group were both lower than NSCLC group (pre-chems) and invalid of chems group. Conclusion Detection of p53 protein in serum has significant value in diagnosis, evaluation of curative effect and prognosis of NSCLC patients.

关键词

p53蛋白/血清/非小细胞肺癌

Key words

p53 protein/ serum/ non-small cell lung cancer

分类

医药卫生

引用本文复制引用

姚坚,陈金亮,陶一江,陈建荣..非小细胞肺癌患者血清中p53蛋白检测的临床意义[J].实用临床医药杂志,2012,16(17):43-45,3.

基金项目

中国高校医学期刊临床专项资金(11220109) (11220109)

实用临床医药杂志

OACSTPCD

1672-2353

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