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天花生物恐怖风险下最优疫苗接种比例

许晴 祖正虎 张文斗 徐致靖 黄培堂 郑涛

军事医学2012,Vol.36Issue(10):736-738,744,4.
军事医学2012,Vol.36Issue(10):736-738,744,4.

天花生物恐怖风险下最优疫苗接种比例

Optimal proportion of immunized populations under different smallpox bioterrorist attack risks

许晴 1祖正虎 1张文斗 1徐致靖 1黄培堂 1郑涛1

作者信息

  • 1. 军事医学科学院生物工程研究所,北京100071
  • 折叠

摘要

Abstract

Smallpox is one of the most dangerous biological agents. Although smallbox has been eliminated globally, the possibility of smallpox being used during a bioterrorist attack still exists. Large-scale smallpox vaccination is the most effective measure against smallpox bioterrorism, but may lead to serious side effects and even death. Therefore, retaining a certain proportion of immunized populations will reduce the overall losses in case of smallpox bioterrorist incidents. Based on minimized quality-adjusted life years losses, this article explored the optimal proportion of immunized populations that a country shoulol retain under the different smallpox bioterrorist attack risks.

关键词

天花/质量调整生命年/接种/疾病传播/仓室模型/生物恐怖

Key words

smallpox/quality adjusted life years/vaccination/disease transmission/component model/bioterrorism

分类

军事科技

引用本文复制引用

许晴,祖正虎,张文斗,徐致靖,黄培堂,郑涛..天花生物恐怖风险下最优疫苗接种比例[J].军事医学,2012,36(10):736-738,744,4.

基金项目

国家自然科学基金资助项目(90924019) (90924019)

"艾滋病和病毒性肝炎等重大传染病防治"国家科技重大专项(2008ZX10403) (2008ZX10403)

军事医学

OA北大核心CSCDCSTPCD

1674-9960

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