江西农业学报2012，Vol.24Issue(10)：127-129,3.
禽多杀性巴氏杆菌、H9亚型禽流感二联灭活疫苗研制及免疫效力试验
Preparation and Test of Binary Inactivated Vaccine against Avian Pasteurella Multocida and Avian Influenza H9
摘要
Abstract
Avian Pasteurella multocida and H9 subtype of avian influenza virus were both isolated by using embryonated egg inoculation. The number of Pasteurella was more than 4×1010 CFU/mL (colony -forming unit) and EID50(50% egg infectious dose) of H9 subtype of avian influenza was more than 109.38/mL. After inactivation, three batches binary vaccine of the Avian Pasteurella and H9 subtype of avian influenza was produced and undergone a series of tests. Results indicated that the physical property, sterility test, and safety test of the vaccine met the standards. After immunizing the experimental chickens and ducks with the vaccine for 21 days, the protective rate of Avian Pasteurella multocida was above 90% and the protective rate of H9 subtype of avian influenza virus was a-bove 85%.关键词
禽多杀性巴氏杆菌/H9亚型禽流感/灭活疫苗Key words
Avian Pasteurella multocida/ H9 avian influenza virus/ Inactivated vaccine分类
农业科技引用本文复制引用
张敬峰,李银,韩凯凯,刘宇卓,赵冬敏,黄欣梅,游园,周小波,谢星星..禽多杀性巴氏杆菌、H9亚型禽流感二联灭活疫苗研制及免疫效力试验[J].江西农业学报,2012,24(10):127-129,3.基金项目
江苏省科技创新与成果转化项目(BH2011064). （BH2011064）
