昆明医科大学学报2012,Vol.33Issue(9):34-37,4.
脉冲射频术与射频热凝术对兔股神经的影响
Influences of Pulsed Radiofrequency and Radiofrequency Hyperthermia on Rabbit Femoral Nerve
李倩烨 1陈华梅 1李吉艳 1张小梅 1赵川2
作者信息
- 1. 昆明医科大学第一附属医院疼痛科,云南昆明650031
- 2. 昆明医科大学第一附属医院病理科,云南昆明650031
- 折叠
摘要
Abstract
Objective To study the influences on femoral nerve and its surrounding tissue of pulsed radiofrequency (PRF) and radiofrequency hyperthermia (RFTC). Methods Twenty rabbits were selected and randomly divided into 5 groups (4 rabbits in each group). The PRF was applied to the femoral nerve of rabbits in the PRF group at 42 t for 120 s (T42 group) with the pulsed frequency of 2 Hz and T42 group repeat the same steps as T42 group. The RFTC was respectively used to the same tested part of rabbits in the RFTC group at 50 t (T50 group) , 70 t (T70 group) and 80 t (Tgo group) for 120 s. The femoral nerve of rabbits was removed for pathological examination under optical microscope. Results In T42 group, lots of nerves of rabbits were undamaged under optical microscope, only a little heat damage presented on some nerve envelope. Partial heat damage also occurred in T42 group. Focal hot damage of nerve envelop was found in T50 group. Heat destroys, putrescence and fragmentation of nerve envelop and nerve tract were detected, and myelin sheath and axonal injury were discovered in T70 and Tgo group. Conclusions The serious permanent damage of nerves and surrounding tissues is induced by RFTC. PRF causes slight body lesion and is a new safer treatment method for pain than RFTC. The tested results indicate that the analgesic effect of RFTC is achieved by damaging nerves.关键词
脉冲射频/射频热凝/股神经/疼痛治疗Key words
Pulsed radiofrequency/ Radiofrequency hyperthermia/ Femoral nerve/ Pain management分类
医药卫生引用本文复制引用
李倩烨,陈华梅,李吉艳,张小梅,赵川..脉冲射频术与射频热凝术对兔股神经的影响[J].昆明医科大学学报,2012,33(9):34-37,4.