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冠心病合并糖尿病患者体内血小板活化标志物表达的意义

王京 王晨霞 高燕

昆明医科大学学报2012,Vol.33Issue(9):118-121,4.
昆明医科大学学报2012,Vol.33Issue(9):118-121,4.

冠心病合并糖尿病患者体内血小板活化标志物表达的意义

Significance of Platelet Activation Markers Expression in Patients with Coronary Heart Disease Complicated with Diabetes

王京 1王晨霞 1高燕1

作者信息

  • 1. 延安大学附属医院心内二科,陕西延安716000
  • 折叠

摘要

Abstract

Objective To explore the significance of platelet activation markers expression in patients with coronary heart disease complicated with diabetes. Methods Flow cytometry was used to detect the expression of CD62p and PAC-1 in patients at admission, 14 d after treatment or before discharge, and the changes of the expression levels were observed. Automatic biochemistry analyzer was used to test the levels of plasma glucose and lipids. Results The levels of fasting plasma glucose were gradually increased with the progression of disease. The levels of plasma glucose were positively correlated with the concentration of PAC-1 and CD62p. Conclusion The plasma levels of PAC? and CD62p are significantly higher in patients with coronary heart disease complicated with diabetes than patients without diabetes, and are positively correlated with the levels of plasma glucose.

关键词

冠心病/糖尿病/血小板活化

Key words

Coronary heart disease/ Diabetes/ Platelet activation

分类

医药卫生

引用本文复制引用

王京,王晨霞,高燕..冠心病合并糖尿病患者体内血小板活化标志物表达的意义[J].昆明医科大学学报,2012,33(9):118-121,4.

昆明医科大学学报

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