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组织工程修复及不同加力时间点对正畸移动牙牙周BMP 表达的影响

李飒 任康雄 刘华 熊国平 袁理

临床口腔医学杂志2012,Vol.28Issue(10):586-588,3.
临床口腔医学杂志2012,Vol.28Issue(10):586-588,3.DOI:10.3969/j.issn.1003-1634.2012.10.003

组织工程修复及不同加力时间点对正畸移动牙牙周BMP 表达的影响

Effect of tissue engineering and different orthodontic force loading time on expression of periodontal BMP of orthodontic moved teeth

李飒 1任康雄 1刘华 2熊国平 1袁理1

作者信息

  • 1. 暨南大学第二临床医学院,深圳市人民医院口腔医学中心,广东,深圳,518020
  • 2. 广东药学院医药信息工程学院,广东,广州,510006
  • 折叠

摘要

Abstract

Objective: To analyze the effect of tissue engineering and different orthodontic force loading time on expression of periodontai BMP of orthodontic moved teeth. Method: 20 New Zealand rabbits with chronic periodontitis were di-vided into two groups randomly. After tissue engineering and GTR therapy on the chronic periodontitis, the rabbits of one group (20-day group) were loaded orthodontic force on affected teeth 20 days later while the rabbits of another group were the control group. 30 days later all the animals were sacrificed and expression of BMP were analyzed. Result: Average expression of BMP of 20-day group was 4.522?.057, average expression of BMP of 40-day group was 4.321?.071, and average expression of BMP of the control group was 3.372?.051. Significant differences were found at each groups. Conclusion: The expressions of periodontai BMP were higher in groups with tissue engineering therapy than that of control group. The expression of periodontai BMP was higher in the 20-day group than that of the 40-day group.

关键词

组织工程/正畸牙移动/牙周骨形成蛋白

Key words

Tissue Eneineerine: Orthodontic Movement/ BMP

分类

医药卫生

引用本文复制引用

李飒,任康雄,刘华,熊国平,袁理..组织工程修复及不同加力时间点对正畸移动牙牙周BMP 表达的影响[J].临床口腔医学杂志,2012,28(10):586-588,3.

基金项目

深圳市科技计划项目200802098 ()

临床口腔医学杂志

OACSTPCD

1003-1634

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