农业生物技术学报2012,Vol.20Issue(7):837-848,12.DOI:10.3969/j.issn.1674-7968.2012.07.015
生物镁离子转运体研究进展
The Development of Magnesium Transport Systems in Organisms
摘要
Abstract
Magnesium is the most abundant divalent cation in cells and acts as a critical role in organism growth and development. It has the largest hydrated radius, the smallest ionic radius, and the highest charge density. It is very important for organism to transport magnesium within or among cells because of its specially chemical and physical characteristics. Previous research focused on structural features, physiological function and pathology of magnesium deficiency, and have made great progress in photosynthesis, activating enzymes, stabilizing genomic, inhibiting aging, alleviating Al toxicity and adjusting N metabolism. Our understanding of magnesium crystal structure, signaling of magnesium stress and cellular homeostasis is still in its infancy. Some magnesium transporters have been cloned from organism, such as prokaryote, yeast, mammal and plant, also analyzed the structure, function and subcelluar localization of this magnesium transporters. According to the different structure or function of this magnesium transports, they are divided into six disparate family: Cobalt resistance A (Cor A), Arabidopsis thaliana magnesium-proton exchanger (AtMHX), cation channal, P-type ATPase, magnesium transport E (MgtE) family and other magnesium transports. The structure or function of different members which belong to the same family appears to be closely related. The CorA family is the most extensively studied magnesium transport system, and appears to be the primary magnesium transport system, which exists widely in fungi, bacteria, animals and plants with effectively mediating both influx and efflux of magnesium. This paper reviews the research progress of those magnesium transporter systems, and aims to provide some useful references for the later research.关键词
细菌/酵母/动物/植物/镁/镁离子转运体Key words
Bacterium/ Yeast/ Mammal/ Plant/ Magnesium/ Magnesium transporter引用本文复制引用
丛悦玺,骆东峰,陈坤明,蒋立希,郭万里..生物镁离子转运体研究进展[J].农业生物技术学报,2012,20(7):837-848,12.基金项目
中央高校基本科研业务费专项资金(No.2009QNA6033)、浙江大学优秀青年教师资助计划(紫金计划)(No.3A6000*172210101/048)和国家自然科学基金(No.30871469) (No.2009QNA6033)