强激光与粒子束2012，Vol.24Issue(12)：2970-2974,5.DOI:10.3788/HPLPB20122412.2970
基于蒙特卡罗方法的α粒子细胞S值计算
Calculation of cellular S values for α particle based on Monte Carlo simulation
摘要
Abstract
In the case of radiation therapy and BNCT, alpha particles transport the energy to human tissue by second electrons. However, in cellular scale alpha sources do not have a uniform distribution. In order to get the target dosimetry discrepancy by different source locations, a computational application to calculate the S value with Monte Carlo toolkit Geant4 was programmed. S values of two dimensions, twelve energies, and three source locations were calculated. Compared with MIRD results, the difference between both is within 1%. Geant4 toolkit to calculate the cell dosimetry was proved to be believable and flexible. A couple of S values of alpha particles produced in BNCT with 1. 47 MeV and 1. 78 MeV were calculated. To some extent these values can become reference values in clinical therapy.关键词
微剂量/蒙特卡罗方法/α粒子/S值/硼中子俘获治疗Key words
microdosimetry/ Monte Carlo method/ alpha particle/ S value/ BNCT分类
医药卫生引用本文复制引用
谢芹,耿长冉,陈飞达,汤晓斌,姚泽恩..基于蒙特卡罗方法的α粒子细胞S值计算[J].强激光与粒子束,2012,24(12):2970-2974,5.基金项目
江苏省博士后科研计划项目(1002012C) （1002012C）
