山东医药2012,Vol.52Issue(37):7-10,4.
超促排卵过程中加用电针干预对体外受精—胚胎移植患者妊娠结局的影响
Influence of using electro-acupuncture during COH on the pregnancy outcome in patients undergoing in-vitro-fertilization and embryo transfer
摘要
Abstract
Objective To investigate the effects of electro-acupuncture(EA) treatment during COH on oocyte quality and the pregnant outcome of the patients undergoing in-vitro- fertilization and embryo transfer (IVF-ET). Methods Totally 224 patients undergoing IVF-ET, in which, there was 141 cases with PCOS, 83 cases with no-PCOS. They were divided into EA group and control group randomly. They all were given ethinylestradiol and cyproterone acetate tablets and long program ovarian hyperstimulation with gonadotropin-releasing hormone agonist. At the same time, the EA group received EA treatment, and the pregnancy outcome of the two groups was compared. Results The pregnancy rate in EA group of POCS patients was increased by 10. 78% than that in control group, and the fertilization rate, egg spliting rate, high grade oocyte rate were increased significantly in EA group( all P < 0.05). But there were no obvious changes in two groups of no-POCS about those indexes. The levels of SCF in serum, liquor folliculi of pregnancy group were higher than those of non-pregnancy group obviously (all P <0.05). Conclusions Electro-acupuncture used in COH can increase the pregnancy rate in P-COS patients undergoing IVF-ET. The PCOS patients were more sensitive to electro-acupuncture stimulus than the no-PCOS patients.关键词
多囊卵巢综合征/体外受精—胚胎移植/电针/干细胞因子Key words
polycystic ovary syndrome/ in-vitro-fertilization and embryo transfer/ electro-acupuncture/ stem cell factor分类
医药卫生引用本文复制引用
崔薇,李静,孙伟,闻姬,冯晓军..超促排卵过程中加用电针干预对体外受精—胚胎移植患者妊娠结局的影响[J].山东医药,2012,52(37):7-10,4.基金项目
国家自然科学基金资助项目(30973790). (30973790)